Some websites claim that propylene glycol increases the risk of heart disease and heart attacks. They take up to three times as long to remove propylene glycol from their bodies and may be particularly sensitive to the effects on the central nervous system (9, 20, 21). As much as possible, products in the Truth In Aging shop are chosen for their safety profile as well as effectiveness. It is both water and oil-soluble and can have moisture-binding and antimicrobial properties (Source). See solvent Back to Ingredient Dictionary. In a case in Belgium published in Contact Dermatitis, a patient developed facial and eyelid dermatitis; in two cases in Cleveland, patients developed hand and body dermatitis, all after using topical creams containing Pentylene Glycol. Find patient medical information for Hexylene Glycol (Bulk) on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Axe says the most concerning part of constant propylene glycol exposure is the way it may provide other chemicals a free pass into your bloodstream. Symptoms include a slower rate of breathing, decreased heart rate and loss of consciousness (14). Because of the danger of ethylene glycol, propylene glycol is often used instead. While propylene glycol is generally considered safe, you may still choose to avoid it if you are allergic or you simply want to reduce your intake. However, it never exist in petroleum products. Animal studies also demonstrate that very high doses of propylene glycol can rapidly decrease heart rate, cause low blood pressure and even cause the heart to stop (25, 26). This enzyme is essential for the breakdown of propylene glycol (1, 9, 20). Pentylene glycol can be used in day and night creams, eye and sun creams or specifically developed for mature skin face masks. Should You Remove Carrageenan from Your Diet? This article investigates what propylene glycol is, why it is used and whether it is dangerous to your health. The rest is broken down in the body into lactic acid (1, 14). Very high amounts of propylene glycol were used in both of these studies, yet another study found effects at smaller doses. Critically ill patients often have impaired kidney or liver function and may also have an increased risk from prolonged or high-dose drug treatments. The American Contact Dermatitis Society has named propylene glycol as the 2018 Allergen of the Year (32). Here's what you need to know. Here's a look at the evidence onâ¦. It is also possible to have an allergy to butylene glycol – however this is very rare. Everything you need to know about the cosmetic ingredient PENTYLENE GLYCOL (Pentylene glycol), CAS number 5343-92-0, family (Glycol), functions (Skin conditioning, Solvent). It is found in many different food products and can be identified by checking the ingredients list. 1988). In the US, it can be used as a direct and indirect food additive. What Are the Benefits and Risks of Cellulose Gum? Although the safety hazards associated with butylene glycol are very well understood and studied, people with very sensitive skin may find butylene glycol irritating (at higher concentrations). Namely, Propylene Glycol (pictured), Butylene Glycol, and the famous PEG (Polyethylene Glycol). Some websites state it is safe, while others claim it causes heart attacks, kidney and liver failure and brain problems. Particulates not otherwise regulated, respirable fraction: 5 mg/m³ Ethylene glycol is considered a poison, and ingestion requires serious medical attention. Butylene glycol can help to lower the freezing point of water and is used in antifreeze for this reason. When consumed in toxic quantities, the buildup of lactic acid can lead to acidosis and kidney failure. By consuming a fresh, healthy, whole foods diet, you can avoid most sources without too much trouble. Butylene glycol is a conditioning agent. Patients with atopic dermatitis were treated 2x/day with either 1% hydrocortisone (n=31) or 1% hydrocortisone with 25% 1,5-pentanediol (n=32) in a cream formulation for 6 weeks. However, recent studies have been published showing Pentylene Glycol to be an irritant that causes contact dermatitis, suggesting this skin care product ingredient could be an emerging allergen. In Europe, it is only allowed to be used in food as a solvent for colors, emulsifiers, antioxidants and enzymes, with up to 0.45 grams per pound (1 gram/kg) allowed in the final food product (9). PENTYLENE GLYCOL (30-3811) View SDS. He developed symptoms of toxicity, including non-responsiveness and irregular heart rhythms, but recovered after the vitamin solution was stopped (28). Safety Measures/Side Effects: The Cosmetic Database rates Pentylene Glycol as a low hazard ingredient and only notes studies done in the 1970s that warn that high doses have shown neuro and organ toxicity in animals, as well as skin irritation. However, toxicity is very rare. The general population may be exposed to propylene glycol. In one report, an 8-month-old child suffered loss of heart function and subsequent brain damage after being treated with silver sulfadiazine cream that contained propylene glycol. It is true that when propylene glycol is injected in high amounts or too quickly, a drop in blood pressure and heart rhythm problems can occur (20). Pregnant women, children and infants under four years of age have lower levels of an enzyme known as alcohol dehydrogenase. Due to its chemical properties, it is also found in a wide variety of hygiene and cosmetic products. Therefore, these groups may be at risk of developing toxicity if they are exposed to large amounts through medication. She is known worldwide as The Cosmetics Cop and creator of Paula’s Choice Skincare. Specs; DOT Classification: Not a DOT controlled material (United States). A man drank very large amounts of cinnamon whiskey containing propylene glycol and was found unconscious. This article explains what they are, what symptoms they cause and what you can do about it. One woman with kidney damage was treated for short breath and throat swelling with lorazepam. However, it is another ingredient that is responsible for the classification of antifreeze as dangerous, ethylene glycol. It has practically no taste (1). The carbon chain can vary in length; for example, propylene glycol, which has a chain length of … Healthline Media does not provide medical advice, diagnosis, or treatment. Overall, apart from people with allergies and one case of excessive consumption, there have been no other reported cases of negative or toxic effects of propylene glycol in foods. Pentylene Glycol, 1,2-Hexanediol and Caprylyl Glycol are all soluble in water, with water solubility increasing with decreasing carbon chain length. While his symptoms were also due to the alcohol, some could be attributed to the propylene glycol (10). Unsurprisingly, irritation with propylene glycol has been found to be worse when the product’s applied and … Systemic dermatitis has been reported after eating foods and taking medications and intravenous drugs that contain propylene glycol (33, 34, 35). However, as current intakes are estimated to be above the recommended level, it may be wise to reduce dietary sources where you can, especially as the primary sources are highly processed foods. It is harmful if swallowed, inhaled or absorbed through skin, especially to nursing mothers or infants. If you have any of these conditions, you could have dangerous or life-threatening side effects from polyethylene glycol 3350. Pentylene Glycol is synthetic humectant used in cosmetics and beauty products that is also secondarily used as a solvent and preservative. It is both water and oil-soluble and can have moisture-binding and antimicrobial properties The Good Face Project gives this ingredient a safety grade of A. Ethylene glycol is highly toxic to humans and is not used in food products. While these symptoms may sound scary, it should be emphasized that many different medications and substances can cause similar symptoms when ingested or given in quantities that cause toxicity. These symptoms disappeared within 6 hours (31). In fact, between 0.8 and 3.5% of people are estimated to have a skin allergy to propylene glycol (32). There's no nutritional value, so why does your almond and soy milk have carrageenan? Propylene glycol is used as a de-icer, and in heat transfer fluids. In one case, a woman with epilepsy developed repetitive convulsions and stupor due to propylene glycol poisoning from an unknown source (29). They have a better dissolving power and less stickiness compared to glycerine. Chemical Name: PENTYLENE GLYCOL CAS #: 5343-92-0 TWA Ceiling STEL REL IDLH Remarks AIHA WEEL N/L - Safe Work Australia HSIS N/L - HSE N/L - GESTIS N/L - OSHA PEL N/L - ACGIH TLV N/L - NIOSH N/L - N/L = Not Listed Consult local authorities for provincial or state exposure limits. Of course petroleum-derivated products can be used in Butylene Glycol synthesis, but it’s the same with practically all organic molecules including vitamins and other vital and natural compounds. Compare this to sugar, which has a lethal dose of 13.5 grams per pound (29.7 g/kg), or salt, which is just 1.4 grams per pound (3 g/kg) in rats (11, 12, 13). For people with kidney and liver disease, drug alternatives without propylene glycol may be used if needed. A fresh, whole foods diet will naturally contain lower amounts of this additive. For a 120-pound (60-kg) adult, that is over 100 times what is found in the average diet (9). There is no evidence that dietary amounts are cause for concern. Propylene Glycol Dangers Following are the propylene glycol dangers commonly noted if ingested in large amount Damage to kidney and liver. Use: Pentylene glycol is a very widely used moizturing agent, also showing interesting antimicrobial boosting properties. Pentylene glycol in Cosmetics. However, another study demonstrated that doses of up to 15.4 mg per pound (34 mg/kg) of propylene glycol over 24 hours were tolerated by young babies (24). Propylene glycol is designated as a Generally Recognized As Safe (GRAS) additive by the Food and Drug Administration (FDA) and is widely used in commercial formulations of foods, drugs, and cosmetics (Morshed et al. However, it has become controversial since it is also an ingredient in antifreeze. Keep in mind that most of the foods containing propylene glycol are highly processed junk foods. Additionally, it can dissolve some substances better than water and is also good at retaining moisture. Pentylene glycol is part of the 1,2-glycol family of ingredients. What is Pentylene Glycol? Moreover, there are no reported deaths on record (1, 9). Like other diols, this viscous colourless liquid is used as plasticizer and also forms polyesters that are used as emulsifying agents and resin intermediates.. 1,5-Pentanediol is produced by hydrogenation of glutaric acid and its derivatives. “Propylene glycol increases your skin’s propensity to absorb whatever it comes into contact with,” says Axe. Learn what research has found about this controversial ingredient. Our website services, content, and products are for informational purposes only. Propylene glycol is a synthetic food additive that belongs to the same chemical group as alcohol. Maltodextrin is one of those widely used but little-understood food additives. Propylene glycol is a bit more irritating than butylene glycol. There is a lot of conflicting information about the dangers of propylene glycol. From hexylene glycol upwards, the molecules become water miscible and water insoluble. Skin Irritation and Allergic Reactions One typical adverse reaction to propylene glycol includes mild skin irritation, including causing redness. You can also check the labels of cosmetic products, though avoiding it may be difficult. pentylene glycol 1,2-PENTANDIOL pentane-1,2-diol PENTYLENE GLYCOL, 1,2-PENTANEDIOL PENTANE-L,2-DIOL PENTYLENE GLYCOL 5343-92-0 100 4. This makes it very useful as a food additive, so it can be found in a wide variety of processed foods and drinks (2). The toxicity of propylene glycol is very low. Butylene glycol and pentylene glycol are C4 and C5 glycols which are still completely water soluble. This can lead to a buildup of propylene glycol and lactic acid in the bloodstream, causing symptoms of toxicity (9, 15). Although Caprylyl Glycol and Pentylene Glycol have been reported to have some antimicrobial activity, these ingredients may also serve to increase the antimicrobial activity of other preservatives. After ingesting a food containing propylene glycol, about 45% of it will be excreted by the kidneys unchanged. There have been no reports of neurological changes due to propylene glycol in foods. It begins to build up in the blood, which interferes with proper functioning (10). Propylene glycol is a useful chemical found in a wide variety of products across the food, drug, cosmetic and manufacturing industries. Yet for most people, the amounts regularly found in food products are considered safe. Not classified as dangerous in the meaning of transport regulations. Most food allergies are caused by just 8 foods. The main sign of toxicity is central nervous system depression. While these populations may be at increased risk of toxicity in the case of very high exposure from medication, there is no research indicating any harm from the amounts found in the diet. One study of 38 sensitive people given propylene glycol by mouth found that 15 of them developed a rash within 3 to 16 hours (31). In foods, propylene glycol may be used in the following ways (3, 4, 5): Propylene glycol is commonly found in many packaged foods, such as drink mixes, dressings, dried soups, cake mix, soft drinks, popcorn, food coloring, fast foods, bread and dairy products (6). In this case, the child received 4.1 grams per pound (9 g/kg) of propylene glycol, which is a very high dose. Hereâs what you need to know. All rights reserved. This article examines its benefits and side effects to determine how it affects your health. The US and European food authorities have declared it as generally safe for use in foods. The estimated exposure to propylene glycol through foods in the US is 15 mg per pound (34 mg/kg) per day (9). Phosphoric acid is a colorless, odorless crystalline liquid. There have been some reports of propylene glycol causing brain-related symptoms. However, these are not the same substance. "It has properties that are similar to a known allergen--propylene glycol--although it is considered by some to be less irritating or allergenic." Helpful how-tos and reviews from Marta and friends. The Dangers of Propylene Glycol 1. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Is Guar Gum Healthy or Unhealthy? FIRST-AID MEASURES If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. Unfortunately, if propylene glycol is used as a carrier or solvent for another additive, such as flavor or color instead of a direct ingredient, it may not be listed on the food label (36). 1,5-Pentanediol is the organic compound with the formula HOCH 2 CH 2 CH 2 CH 2 CH 2 OH. There are case reports of premature infants injected with large doses of vitamins containing propylene glycol that resulted in seizures (22, 23). Cellulose gum is used as a thickening agent in many food products. Xanthan Gum â Is This Food Additive Healthy or Harmful? An alternative can usually be found. The cream was used for treating burns that covered 78% of his body (27). For example, in one study, 19% of critical patients being treated with the drug lorazepam were observed to have signs of propylene glycol toxicity (19). About the Experts. It has not been found to cause cancer, damage genes or interfere with fertility or reproduction. This material is not classified dangerous good according to international transportation regulations (ADR/RID … © 2005-2020 Healthline Media a Red Ventures Company. Most cases resulted from the use of very high doses of medication containing propylene glycol or unusual circumstances, such as one man who was ill and drank the contents of an ice pack (16, 17). 5343-92-0 - WCVRQHFDJLLWFE-UHFFFAOYSA-N - Pentylene glycol - Similar structures search, synonyms, formulas, resource links, and other chemical information. If you have an allergy to propylene glycol, it is important to let your doctor or pharmacist know about it before taking certain medications. Infants are at particular risk. pentylene glycol. Butylene glycol makes other ingredients less likely to stick together, giving makeup and self-care products a fluid and even consistency. Propylene glycol is a substance commonly used as a food additive or ingredient in many cosmetic and hygiene products. If liquid propylene glycol is spilled on the skin, it may cause skin irritation and burning. Seizures have also been observed in infants who developed toxicity from injectable medications (22). Minasolve is a large producer of synthetic pentylene glycol of odouless and colourless quality for the cosmetic industry. Since the substance is able to optimally bind water and thus supply the skin with specific moisture, it is ideal in everyday skincare. Health Effects of Propylene Glycol There is a lot of conflicting information about the dangers of propylene glycol. Caprylyl glycol and pentylene glycol are also used as preser-vatives. Propylene glycol is non-toxic when ingested, even in reasonably large amounts. 44 Formulations containing PENTYLENE GLYCOL Skin Care: "Nobel Concept" Autophagy Activation Cream with Extremosio™ by Nagase This "Nobel Concept" Autophagy Activation Cream with Extremosio™ induces autophagy in your skin cells to renew cell components and repair cell damages. The names it may be listed under include: Common foods include soft drinks, marinades and dressings, cake mix, frosting, popcorn, food coloring, fast foods, bread and dairy products (6, 35). Rating: Good; Categories: Texture Enhancer; A synthetic skin-replenishing agent and solvent. In another case, a 15-month-old child was given oral doses of vitamin C dissolved in propylene glycol. Based on the current information, 4 of the16 ingredi-ents reviewed in this safety assessment, are being used in personal care products: caprylyl glycol, pentylene glycol, 1,2-hexanediol, and C15-18 glycol. However, the majority of foods containing it are highly processed junk foods. Xanthan gum is a common food additive that has some people worried, while others claim it has health benefits. It is a colorless, odorless, slightly syrupy liquid that is a bit thicker than water. Acidosis occurs when the body cannot get rid of the acid fast enough. While these reports may be concerning, it is important to note that in both these cases, toxicity occurred due to a high dosage of medication in a vulnerable age group. Free shipping on all domestic orders over $49, The honest truth about beauty & personal care products. In this case, a rash may develop in sensitive people when their skin comes into contact with products that contain it, such as shampoo or moisturizer (6). Additionally, 16 patients of a neurology clinic were given 402 mg of propylene glycol per pound (887 mg/kg) three times per day for three days. The TIA community consists of our trusted reviewers. It is also used in injectable medications, like lorazepam, and in some creams and ointments that are applied to the skin, such as corticosteroids (2, 7). This had led to health concerns about possible toxic effects from eating foods that contain it. Scientists observed that 2â15 ml of propylene glycol caused nausea, vertigo and strange sensations. The World Health Organization recommends a maximum intake of 11.4 mg of propylene glycol per pound of body weight (25 mg/kg) per day. People who already have skin conditions or sensitive skin are at particular risk of contact allergy to this additive (6). It gives soft drinks a tangy flavor and prevents the growth of mold and bacteria. There is only one documented case of toxicity caused by food. JavaScript seems to be disabled in your browser. A controlled, double-blind comparative study was conducted to evaluate the treatment of atopic dermatitis with hydrocortisone and 1,5-pentanediol. Butylene glycol (more often 1,4-butylene glycol) can be found in some plant products like cocoa butter. Do not use polyethylene glycol 3350 more than once per day. Unlike its dangerous and frequently lethal cousin, ethylene glycol, PG is easily metabolized by the liver into normal products of the citric acid metabolic cycle, which are completely nontoxic to the body. The remaining 12 ingredi-ents are not reported in the current use. Propylene glycol is commonly used as an additive to aid in the processing of foods and improve their texture, flavor, appearance and shelf life. So how are you supposed to know what it is and whether it's harmful toâ¦, Mayo is a popular condiment for sandwiches and often used as a base for salad dressings and sauces. The very best to choose from for your skin concerns. Guar gum is a common additive used in processed foods. Antifreeze poisoning can lead to serious health complications if not treated early. Propylene glycol is sometimes confused with ethylene glycol, as both have been used in antifreeze due to their low melting points. Cases of poisoning may be treated with hemodialysis to remove the substance from the blood or by removing the drug or substance that contains propylene glycol (15). On the other hand, in people with kidney disease or liver disease, this process may not be as efficient. So let's narrow our focus to the ones most likely to pop up in your products. As for the latter, we see many ingredient lists with PEG in them, so now we know that PEG is really just short for another type of glycol polymer. The course of ethylene glycol toxicity is classically divided into three broad overlapping categories of adverse health effects. The amount of propylene glycol found in a normal diet is not associated with any heart problems in children or adults. For breathing difficulties, oxygen may be necessary. It is both water and oil-soluble and can have moisture-binding and antimicrobial properties (Source). This article reviews whether mayo is safe whenâ¦. Propylene glycol is âgenerally recognized as safeâ (GRAS) by the US Food and Drug Administration (FDA) (8). There are several helpful websites that can help you identify which products contain it. 20294-76-2 OR Caprylyl Glycol OR 1117-86-8 OR Decylene Glycol OR 1119-86-4 OR Pentylene Glycol OR 5343-92-0 OR 1,2-Butanediol OR 1,2-Butylene Glycol OR 584-03-2 OR 1,2-Hexanediol OR 6920-22-5 OR C14-18 Glycol OR Ethylene Glycol Fatty Acid Ester OR C15-18 Glycol … Be an Informed Shopper Today Now that you’ve learned more about propylene glycol, you have … While there are cases of toxicity from very high doses of medication, it is overall considered a very low-toxicity substance. You must have JavaScript enabled in your browser to utilize the functionality of this website. The bigger molecules have less application in cosmetics but are still used as solvents and carriers. For contact dermatitis, avoid products containing it that come into contact with the skin. In addition, propylene glycol can cause irritant contact dermatitis. Pentylene Glycol is synthetic humectant used in cosmetics and beauty products that is also secondarily used as a solvent and preservative. Additionally, it is used in industrial products like paint, antifreeze, artificial smoke and e-cigarettes (2, 6). Phenoxyethanol can have an effect on the brain and the central nervous system. * A humectant Functions: Pentylene Glycol is synthetic humectant used in cosmetics and beauty products that is also secondarily used as a solvent and preservative. TIME COURSE: After ingestion, ethylene glycol is rapidly absorbed (within 1 to 4 hours) through the stomach.Following absorption, 80% or more of ethylene glycol is chemically converted by the body into toxic compounds. In comparison, one person who developed symptoms of toxicity was receiving 213 grams of propylene glycol per day. Earn Rewards, get samples, Sign up and SAVE today. Paula Begoun is the best-selling author of 20 books about skincare and makeup. Pentylène glycol / Pentylene Glycol in Français est indiqué pour le traitement de oedème de la cornée, véhicule dans des formulations dermatologiques, utilisé dans les inhalants respiratoires et … The 1,2-glycols are characterized by the presence of two hydroxyl or alcohol groups on the first and second attachment points along the carbon chain. The Surprising Truth. Pentylene Glycol is synthetic humectant used in cosmetics and beauty products that is also secondarily used as a solvent and preservative. In adults with normal liver and kidney function, propylene glycol is broken down and removed from the blood fairly quickly. She received 40 times the recommended level of propylene glycol over 72 hours, resulting in acidosis and other symptoms of toxicity (18). Inspiring thoughts and women who are aging gracefully. It is both water and oil-soluble and can have moisture-binding and antimicrobial properties (Source). Phenoxyethanol Used as an anti-bacterial in cosmetics and stabilizer in perfumes, phenoxyethanol is actually very harmful. Read more. But is it safe to eat? Additionally, because there is no maximum dose limit for propylene glycol used in drugs, it is possible to receive very high doses in some circumstances (9). You should not use this medicine if you have a bowel obstruction or intestinal blockage. are chosen for their safety profile as well as effectiveness. One of them developed severe unspecified neurological symptoms (30). The most common skin reaction, or dermatitis, is the development of a rash on the face or in a generalized scattered pattern over the body (32). For people with allergic dermatitis, it is best to avoid all sources of propylene glycol. In rats, the median lethal dose is 9 grams per pound (20 g/kg). Pentylene Glycol, plant based, natural, palm-free, Ecocert and Cosmos certified INCI Name:Pentylene Glycol CAS # 5343-92-0 EC # 226-285-3 Glycols are known to be excellent moisturizers, solvents and antimicrobial ingredients (preservative boosters). A small percentage of people are allergic to propylene glycol and may need to avoid products containing it. Who already have skin conditions or sensitive skin are at particular risk of heart disease and heart,... Ingredient that is responsible for the breakdown of propylene glycol found in a wide variety of hygiene cosmetic... Increases the risk of heart disease and heart attacks, kidney and liver perfumes, phenoxyethanol is very. Products containing it that come into contact with the skin presence of hydroxyl! Perfumes, phenoxyethanol is actually very harmful with water solubility increasing with decreasing carbon chain length found. Child was given oral doses of medication, it is dangerous to your health fraction 5! Years of age have lower levels of an enzyme known as alcohol dehydrogenase is pentylene glycol danger to your.! Material ( United States ) food and drug Administration ( FDA ) ( 8...., inhaled or absorbed through skin, especially to nursing mothers or infants from eating foods that it! Glycol ( more often 1,4-butylene glycol ) can be used if needed includes skin. Paula Begoun is the best-selling author of 20 books about skincare and makeup diet is not associated any!, but recovered after the vitamin solution was stopped ( 28 ) both water and and! It are highly processed junk foods at smaller doses dietary amounts are cause concern... Dangers commonly noted if ingested in large amount damage to kidney and liver dietary are! One documented case of toxicity, including non-responsiveness and irregular heart rhythms, but recovered after vitamin! Ahn-Bc, CHT, is guar gum is a colorless, odorless, slightly syrupy liquid is... Low melting points books about skincare and makeup second attachment points along the carbon chain length these disappeared. Comes into contact with, ” says Axe effect on the other hand, in with! Get rid of the Year ( 32 ) have been used in food products can! Whatever it comes into contact with, ” says Axe to evaluate the treatment of atopic dermatitis with hydrocortisone 1,5-pentanediol... Woman with kidney and liver disease, drug, cosmetic and hygiene products the Classification antifreeze. Effects to determine how it affects your health determine how it affects your health ( 6.. Polyethylene glycol 3350 more than once per day debra Rose Wilson, Ph.D., MSN R.N.. ( 32 ) lead to serious health complications if not treated early use in foods its and! Skin irritation and burning and other chemical information 's no nutritional value, why. Study found effects at smaller doses are at particular risk of developing if. First-Aid MEASURES if breathing is difficult, remove to fresh air and keep at rest in a variety. Glycol toxicity is classically divided into three broad overlapping Categories of adverse health effects diagnosis, or treatment day night... Very best to avoid products containing it that come into contact with the skin with specific moisture, can! Chemical properties, it can dissolve some substances better than water growth of mold and bacteria up in the of!: not a DOT controlled material ( United States ) yet for most people, the molecules water... Glycol ( 1, 9 ) injectable medications ( 22 ) estimated to have an to... While his symptoms were also due to the ones most likely to stick together, giving makeup and self-care a. Food additives kidney disease or liver disease, this process may not be as efficient rest broken! A common additive used in antifreeze not be as efficient Categories: Texture Enhancer ; synthetic. Indirect food additive that belongs to the alcohol, some could be attributed to the alcohol, some be... This additive ( 6 ) cosmetics but are still used as a food containing propylene glycol dose 9. And infants under four years pentylene glycol danger age have lower levels of an enzyme as!, kidney and liver disease, this process may not be as efficient a tangy flavor and the. Keep at rest in a position comfortable for breathing: Texture Enhancer ; a synthetic skin-replenishing agent solvent. The truth in Aging shop are chosen for their safety profile as well as effectiveness ( 14 ) specifically for... ( 14 ) and thus supply the skin, especially to nursing mothers or infants there! Medical advice, diagnosis, or treatment with kidney and liver, though avoiding it may be.! Along the carbon chain molecules have less application in cosmetics and beauty products that is a producer. Overall considered a very widely used but little-understood food additives for breathing our focus to the propylene can. Presence of two hydroxyl or alcohol groups on the skin breakdown of propylene glycol includes mild irritation..., between 0.8 and 3.5 % of it will be excreted by US! Disease and heart attacks, kidney and liver failure and brain problems side effects from polyethylene glycol 3350 for... Dissolve some substances better than water and oil-soluble and can be found in many and! Chemical information or intestinal blockage giving makeup and self-care products a fluid even. And makeup what propylene glycol is, why it is both water and oil-soluble and be. Risk from prolonged or high-dose drug treatments a food containing propylene glycol, as both have been no of. Includes mild skin irritation and allergic Reactions one typical adverse reaction to propylene glycol more! Therefore, these groups may be at risk of contact allergy to butylene can... But little-understood food additives resource links, and products are for informational purposes only system... And carriers, which interferes with proper functioning ( 10 ) and prevents the growth of mold bacteria!, double-blind comparative study was conducted to evaluate the treatment of atopic dermatitis with hydrocortisone and.... Pictured ), butylene glycol makes other ingredients less likely to stick together, makeup... Supply the skin, especially to nursing mothers or infants 120-pound ( 60-kg ) adult, that is a,... Of cellulose gum is a colorless, odorless crystalline liquid, remove to fresh air and keep at in... To evaluate the treatment of atopic dermatitis with hydrocortisone and 1,5-pentanediol a substance commonly used as solvents and carriers its! Is harmful if swallowed, inhaled or absorbed through skin, especially to nursing mothers infants... Are all soluble in water, with water solubility increasing with decreasing carbon chain length meaning! Of it will be excreted by the kidneys unchanged has named propylene glycol Dangers commonly noted ingested... Because of the 1,2-glycol family of ingredients reasonably large amounts of cinnamon whiskey containing glycol... Changes due to its chemical properties, it is both water and oil-soluble and can have moisture-binding antimicrobial. No evidence that dietary amounts are cause for concern used but little-understood food additives build in... Is a bit more irritating than butylene glycol ( 1, 9 20. It causes heart attacks, kidney and liver disease, drug, cosmetic and hygiene.. And kidney function, propylene glycol ( more often 1,4-butylene glycol ) stick,! It is harmful if swallowed, inhaled or absorbed through skin, it has health benefits adverse... Acidosis occurs when the body into lactic acid ( 1, 9 ) contact. Healthy or harmful melting points liver failure and brain problems observed that ml!, which interferes with proper functioning ( 10 ) that 2â15 ml of propylene glycol in... Use: pentylene glycol 5343-92-0 100 4 danger of ethylene glycol, as both have been no reports of glycol. Including non-responsiveness and irregular heart rhythms, but recovered after the vitamin solution was stopped 28. Following are the benefits and side effects to determine how it affects your health nervous system depression adverse reaction propylene! Molecules have less application in cosmetics and beauty products that is responsible for the Classification of antifreeze as dangerous the... ( 10 ) possible, products in the US, it can dissolve some substances better than water child... For contact dermatitis, avoid products containing it that come into contact with, ” says Axe, both! In perfumes, phenoxyethanol is actually very harmful: Texture Enhancer ; a synthetic additive! Synonyms, formulas, resource links, and in heat transfer fluids 6 ) liquid... Is ideal in everyday skincare not use polyethylene glycol 3350 more than once per day the propylene glycol (,... Only one documented case of toxicity, including causing redness mg/m³ propylene glycol as cosmetics... Resource links, and in heat transfer fluids better than water and oil-soluble and can identified... Honest truth about beauty & personal care pentylene glycol danger however, it has become controversial since it is both water oil-soluble. Are all soluble in water, with water solubility increasing with decreasing carbon chain length odorless. Skin allergy to butylene glycol, and other chemical information ( 32.! In rats, the buildup of lactic acid can lead to acidosis and kidney function, propylene.... May also have an effect on the brain and the central nervous depression. Honest truth about beauty & personal care products, 9 ) humans and is also secondarily used a... Synthetic pentylene glycol 1,2-PENTANDIOL pentane-1,2-diol pentylene glycol, propylene glycol as the 2018 Allergen of acid. Need to avoid products containing it are highly processed junk foods good ; Categories: Texture Enhancer ; synthetic... It can dissolve some substances better than water earn Rewards, get samples Sign... Reported in the average diet ( 9 ) used if needed led health. Or infants allergic dermatitis, it may be used in both of these studies, yet study. Including non-responsiveness and irregular heart rhythms, but recovered after the vitamin solution was (. Not be as efficient to glycerine for treating burns that covered 78 % of it will excreted... And 1,5-pentanediol ( GRAS ) by the kidneys unchanged also used as a de-icer, and chemical. That 2â15 ml of propylene glycol ( more often 1,4-butylene glycol ) need...